Alice awakes in Raccoon City, only to find it has become infested with zombies and monsters. With the help of Jill Valentine and Carlos Olivera, Alice must find a way out of the city before it is destroyed by a nuclear missile.
Alice terbangun di Raccoon City, yang telah penuh dengan zombie dan monster. Dengan bantuan Jill Valentine dan Carlos Olivera, Alice harus menemukan jalan keluar kota sebelum dihancurkan oleh rudal nuklir.